Pavla Lužná, PhD.

phone:585 632 266
Pavla Lužná, 3. 7. 1983
2001–2004 Biochemistry, Faculty of Natural Sciences, Palacky University Olomouc (Bc.)
2004–2006 Biochemistry, Faculty of Natural Sciences, Palacky University Olomouc (MSc.)
2006–2013 PhD. study, Field: Anatomy, Histology, Embryology, Faculty of Medicine and Dentistry, Palacky University Olomouc
2008- up to now Researcher, Dept of Histology and Embryology, Dept of Biology, Faculty of Medicine and Dentistry, Palacky University Olomouc
  1. Educational activities:
    seminars: Basic Histochemistry (HIE/VCB21; HIE/VAB21); Molecular Pathology (LRR/MOPA)
    practical classes: Histology and Embryology I, II (HIE/VCB11; HIE/VCA12; HIE/VAB11; HIE/VAA12)
  2. Scientific interests: carcinogenesis, inflammation processes, DNA damage, immunohistochemistry, miRNA, real-time PCR
  3. Scientific and research activities:
    • co-researcher in MSM6198959205 project - Studies of genes and molecular mechanisms involved in regulation of hematopoiesis, their clinical impact and targeted treatment; investigator prof. MUDr. Karel Indrák, DrSc. (2005-2011)
    • co-researcher in IGA MZČR NS10279-3 project - New possibilities of prediction of Barrett´s oesophagus carcinogenesis; investigator prof. MUDr. Jiří Ehrmann, Ph.D. (2009-2011)
    • co-researcher in IGA MZČR NT11049 project - Gene expression profiling of the periprosthetic tissues: first step toward time-dependent analysis of periprosthetic osteolysis; investigator doc. MUDr. Jiří Gallo, Ph.D. (2010-2014)
    • co-researcher in LF_2012_016 project – Molecular substance and diagnostic markers of selected hematological and system diseases III; investigator doc. RNDr. Vladimír Divoký, Ph.D. (2012)
    • co-researcher in LF_2012_019 project – Studies of cell damage and cell signaling in relation to their potential diagnostic and therapeutic utilization; investigator Ing. Ivo Überall, Ph.D. (2012)
    • co-researcher in OPVK CZ.1.07/2.2.00/28.0066 project – Progress and internationalization of chemical and biological study programmes at Palacky University Olomouc; investigator prof. RNDr. Zdeněk Dvořák, Ph.D. (2012-2014)
    • co-researcher in IGA MZČR NT13587 project - Molecular pathophysiology of selected inborn erythropoiesis errors; investigator doc. RNDr. Vladimír Divoký, Ph.D. (2012-2015)
    • main investigator in GAČR 14-10687P – Expression of inflammatory cytokines in hematopoietic tissue of primary polycythemia (2014-2016)
  4. Publication activities: : 5 original papers, 1 review, 1 chapter in book, 4 lectures, 18 poster presentations
  5. Citations: 48 (H-index 3)
  6. Further activities: Education in subjects „Histology a histological technique“ and „Practical classes in histology and histological technique“ in E. Pötting Grammar Medical School in Olomouc
  7. Publications:
    • Lužná P, Ehrmann J Jr, Laser capture microdissection and its practical applications, Cesk Patol 49 (2013) 123.
    • J. Gregar, V. Procházka, P. Lužná, J. Ehrmann Jr, Využití NBI v diagnostice a sledování pacientů s Barrettovým jícnem, Gastroent Hepatol 66 (2012) 165.
    • S. Takacova, R. Slany, J. Bartkova, V. Stranecky, P. Dolezel, P. Luzna, J. Bartek, V. Divoky, DNA Damage Response and Inflammatory Signaling Limit the MLL-ENL-Induced Leukemogenesis In Vivo, Cancer Cell 21 (2012) 517.
    • P. Luzna, J. Gregar, I. Uberall, L. Radova, V Prochazka, J. Ehrmann, Changes of microRNAs-192, 196a and 203 correlate with Barrett's esophagus diagnosis and its progression compared to normal healthy individuals, Diagn Pathol 6 (2011) 114.
    • P. Luzna, D. Kylarova, M. Novak, V. Lichnovsky, Hematopoietic stem cell separation for experimental purposes – methodic limitations, Biomed Pap 153 (2009) 121.
    • P. Jancova, E. Anzenbacherova, B. Papouskova, K. Lemr, P. Luzna, A. Veinlichova, P. Anzenbacher,V. Simanek, Silybin is metabolized by cytochrome P4502C8 in vitro, Drug Metab Dispos 35 (2007) 2035.

Last update: June 2014